CBD Oil for Shift Work Sleep Disorder: Chronic Circadian Recovery | PureCraft CBD
By PureCraft Editorial Team | PureCraft CBD | Updated October 2026
Shift work sleep disorder (SWSD) is not jet lag. It is not general fatigue. It is a clinically recognized circadian rhythm disorder that affects millions of nurses, factory workers, truck drivers, emergency responders, and anyone whose schedule routinely overlaps with the hours when the human body expects to sleep. Unlike jet lag, which resolves on its own once travel ends, SWSD is chronic, ongoing, and structurally embedded in a person's livelihood. It does not go away when the weekend arrives. It accumulates.
This guide explores the science of SWSD, how it differs from acute circadian disruption, why the endocannabinoid system (ECS) is chronically stressed in shift workers, and how CBD oil may support sleep quality, recovery, and long-term wellbeing for people living against their biology's clock.
What Is Shift Work Sleep Disorder — and Why It's Serious
Shift work sleep disorder is defined by the International Classification of Sleep Disorders, Third Edition (ICSD-3) as insomnia and/or excessive sleepiness occurring in relation to a work schedule that overlaps with the usual sleep period — persisting for at least three months. It is not simply "being tired from working nights." It is a persistent desynchronization between external schedule demands and the internal circadian clock anchored in the suprachiasmatic nucleus (SCN) of the hypothalamus.
Approximately 15–20% of the US workforce works non-traditional hours. Of those, estimates suggest 10–38% meet clinical criteria for SWSD, with many more experiencing subclinical symptoms that impair quality of life without reaching diagnostic threshold.
Who Is Most Affected
Not all shift workers are equally affected. Fixed night shift workers face one set of challenges — their body can partially adapt over weeks to a consistently shifted schedule if light management is practiced rigorously. But rotating schedule workers face the hardest situation of all: the body begins adapting to the night schedule, and then the schedule rotates back before adaptation is complete. This creates perpetual desynchrony with no stable phase anchor. Early morning shift workers are forced into extreme phase advances — going to bed at 8 or 9pm — that conflict with the social evening light exposure most people cannot avoid. Split shift workers accumulate fragmented sleep across multiple short windows.
The Real Health Consequences of SWSD
What makes SWSD a serious public health issue — not merely a quality-of-life inconvenience — is its association with significant long-term health consequences:
Sleep debt accumulation: Shift workers average 2–4 fewer hours of sleep per day than day workers. Over weeks and months, this creates chronic sleep debt with measurable cognitive impairment — slowed executive function, reduced reaction time, impaired working memory, and decision-making deficits comparable to legal intoxication levels in some studies.
Metabolic disruption: The circadian clock governs insulin secretion, glucose metabolism, and appetite hormones. Misaligned feeding and fasting cycles in shift workers are strongly associated with insulin resistance, obesity, and increased type 2 diabetes risk — independent of diet composition.
Cardiovascular risk: Chronic cortisol elevation, autonomic nervous system dysregulation, and systemic inflammation elevate cardiovascular disease risk. Long-term night shift work is associated with higher rates of hypertension, coronary artery disease, and stroke.
Cancer risk: In 2007, the World Health Organization's International Agency for Research on Cancer (IARC) classified night shift work as "probably carcinogenic to humans" (Group 2A), primarily due to chronic melatonin suppression disrupting immune surveillance and promoting cell proliferation. This classification remains in effect.
Mental health burden: Shift workers have significantly elevated rates of depression, anxiety, and occupational burnout. Social isolation — being out of phase with family schedules, social rhythms, and daylight — is a chronic stressor with real psychological consequences. See our guides on CBD oil for depression and CBD oil for anxiety for more on these downstream effects.
Gastrointestinal disruption: The gut has its own peripheral circadian clock, governing motility, enzyme secretion, and microbiome composition. Chronic circadian misalignment is associated with increased rates of irritable bowel syndrome, peptic ulcers, and functional GI disorders among shift workers.
Why the Endocannabinoid System Is Chronically Depleted in Shift Workers
Key Differentiator: SWSD vs. Jet Lag and the ECS
For jet lag, CBD supports an acute, transient disruption of a fundamentally healthy ECS. For shift work sleep disorder, the situation is categorically different: the ECS itself is chronically depleted and dysregulated. This has profound implications for how CBD oil should be used — and why consistent, daily ECS support matters more than situational dosing.
The ECS has its own circadian regulation. Anandamide (AEA) and 2-arachidonoylglycerol (2-AG) — the body's primary endocannabinoids — follow diurnal patterns, with CB1 receptor density fluctuating across the day. Chronic sleep deprivation, sustained HPA axis activation, and systemic inflammation each independently suppress this system.
Here is what chronic shift work does to the endocannabinoid system specifically:
Sleep deprivation depletes endocannabinoid tone: Animal models demonstrate that sustained sleep loss reduces CB1 receptor expression and lowers circulating anandamide levels. The ECS "sleep pressure" signal — a rising anandamide level through the waking period that promotes sleep onset — is disrupted when the waking period is artificially extended or mistimed relative to the light-dark cycle.
Chronic HPA activation suppresses ECS signaling: Cortisol and the ECS are functionally antagonistic. Elevated cortisol — which is chronically elevated in SWSD — suppresses endocannabinoid synthesis and downregulates CB1 receptor sensitivity. The stress-CBD relationship operates through this HPA-ECS axis. Shift workers in a state of chronic cortisol elevation experience a compounding feedback: stress suppresses the ECS, which reduces the ECS's capacity to buffer stress response.
Inflammatory load and CB2 relevance: Chronic circadian misalignment significantly elevates systemic inflammatory markers — interleukin-6 (IL-6), C-reactive protein (CRP), and TNF-α. CBD's CB2-mediated and cytokine-modulating anti-inflammatory actions become especially relevant in this context, not just for sleep but for the broader inflammatory burden that makes shift work a long-term health risk.
Social isolation as a chronic ECS stressor: The psychological burden of "living against society's schedule" — missing family events, being awake when everyone else sleeps, disrupted social bonds — constitutes a chronic psychosocial stressor. Chronic psychosocial stress independently depletes ECS tone through sustained cortisol and inflammatory signaling.
The implication for CBD use is significant: shift workers benefit from consistent daily ECS support, not just situational pre-sleep dosing. This is fundamentally different from the jet lag use case, where acute pre-sleep support is the primary strategy.
The Rotating Schedule Problem
Fixed Night Shift vs. Rotating Schedule: A Critical Distinction
Fixed night shift: The body has the biological capacity to partially adapt to a consistently shifted schedule over two to four weeks. With rigorous light management — bright light exposure early in the night shift, blue-light blocking glasses when commuting home at dawn, complete blackout curtains for daytime sleep — the circadian clock can be progressively phase-shifted toward the new schedule. It is not ideal, but it is manageable. CBD strategy here focuses on facilitating daytime sleep onset and providing pre-shift anxiety relief.
Rotating schedule: The SCN never stabilizes. Every rotation resets whatever partial adaptation has occurred. The body is perpetually in a state of circadian desynchrony with no stable phase anchor. For these workers, the CBD strategy must shift from "circadian resynchronization support" to damage mitigation and daily ECS baseline maintenance.
One additional nuance: clockwise rotation (day shift → evening shift → night shift → back to day) is physiologically easier than counterclockwise rotation. Phase delays — pushing the sleep window later — are easier for the SCN than phase advances (pulling it earlier). When workers have any input into scheduling, clockwise rotation and longer rotation intervals are strongly preferable.
CBD Strategy by Shift Type
The optimal CBD approach differs meaningfully depending on which type of shift schedule a worker maintains. The following table outlines differentiated strategies:
| Shift Type | Primary Problem | CBD Strategy | Key Product |
|---|---|---|---|
| Fixed Night Shift | Daytime sleep difficulty; alertness during night shift | Sleep support before daytime sleep; low-dose CBD at shift start for alertness | CBD+CBN+Melatonin Gummies at sleep time; Oil at shift start |
| Rotating Schedule | Perpetual desynchrony; no stable phase anchor | Damage mitigation; consistent daily ECS baseline; stress/anxiety management | Softgels (daily baseline) + Oil as needed |
| Early Morning Shift | Phase advance difficulty; sleep onset at early bedtime | Sleep onset support at early bedtime; evening light avoidance | CBD+CBN+Melatonin Gummies; Oil 45 min before early bedtime |
| Split Shift | Fragmented sleep; multiple short sleep opportunities | Short-duration sleep quality improvement; nap support with faster offset | Broad Spectrum Oil (faster offset for short naps vs. gummies) |
Light Management and CBD: Complementary Tools
Light First, Then CBD
Light is the most powerful circadian zeitgeber — the primary external signal the SCN uses to anchor the body clock. No supplement, including CBD, overrides light's influence on circadian timing. The evidence-based hierarchy is: light management first, CBD as a complementary tool within that framework.
For night shift workers: Seek bright light exposure during the first half of the night shift (ideally 2,500+ lux or quality artificial bright light); wear blue-light blocking glasses when commuting home after dawn; use complete blackout curtains and white noise for daytime sleep. Only after implementing these measures does CBD+CBN+Melatonin become a meaningful additional tool for sleep onset.
For early morning shift workers: Avoid bright evening light (shift forward your personal "night"); use blue-light glasses from 6–7pm onward; take CBD+CBN+Melatonin 60 minutes before your early bedtime.
CBD oil and our CBD+CBN+Melatonin Gummies work most effectively when light management has already reduced the circadian resistance to sleep at atypical hours.
Critical Timing Note for Shift Workers Using Melatonin
For shift workers, melatonin timing is the opposite of most people's use. Take melatonin and CBD+CBN+Melatonin products when you are beginning your daytime sleep, not at conventional nighttime. Taking melatonin at 10pm when you need to sleep at 8am does nothing useful. The signal needs to arrive when your body needs the sleep onset trigger — which for night shift workers is mid-morning or early afternoon.
CBD for SWSD Comorbidities: The Broader Health Protection Angle
Because SWSD carries significant long-term health consequences beyond poor sleep, a comprehensive CBD strategy for shift workers addresses multiple concurrent concerns:
Inflammation and Immune Function
Chronic circadian misalignment elevates systemic inflammatory markers. CBD's CB2-mediated and cytokine-modulating anti-inflammatory effects provide ongoing support for the elevated inflammatory baseline of chronic SWSD. Additionally, shift workers' impaired immune function — partly a consequence of chronic sleep deprivation and melatonin suppression — makes immune support a meaningful consideration. Our Elderberry Gummies combine CBD with elderberry's well-documented immune-supporting properties for this purpose.
Anxiety, Stress, and Burnout
The psychological burden of chronic SWSD is significant and often underaddressed. CBD's interaction with 5-HT1A serotonin receptors and HPA axis modulation provides a relevant mechanism for the anxiety, stress, and early-stage burnout that many shift workers experience. For workers who find that shift work fatigue is compounding mental health challenges, consistent CBD use addresses both the sleep and the psychological dimensions. Research by Blessing et al. (2015) documented CBD's potential across multiple anxiety-relevant pathways,1 and Shannon et al. (2019) found sleep and anxiety scores both improved in a clinical series.2
Physical Recovery Between Shifts
Many shift work occupations — nursing, emergency response, manufacturing, logistics, transport — involve significant physical demands. Recovery between shifts is compressed by inadequate sleep and short inter-shift intervals. Our CBD Muscle and Joint Cream provides localized support for the musculoskeletal demands of physically intensive shift work. Applied post-shift, it supports recovery during the truncated rest window many shift workers have before returning to work.
Modafinil, Wakefulness Agents, and CBD
Modafinil and armodafinil are FDA-approved for SWSD-related excessive sleepiness and are among the few pharmacological interventions with specific SWSD indications. Many shift workers also use these medications off-prescription. It is important to address the CBD interaction directly.
Both modafinil and armodafinil are metabolized primarily via CYP3A4. CBD is a known CYP3A4 inhibitor. The interaction risk is moderate — CBD may slow clearance of modafinil, potentially increasing its duration of effect and side effect burden. Shift workers combining CBD with modafinil or armodafinil should discuss this with their healthcare provider and monitor for increased modafinil effects. For more context on CBD drug interactions generally, see our CBD oil drug interactions guide.
Critically: CBD is not a substitute for modafinil for on-shift alertness. Low doses of CBD (10–15mg) may have mild alerting or anxiolytic effects that support functional alertness, but CBD is not a wakefulness-promoting agent in the pharmacological sense that modafinil is. It does not reliably override severe sleep deprivation-induced cognitive impairment. Shift workers who need to be sharply alert for safety-critical tasks — driving, operating machinery, patient care — should not rely on CBD for wakefulness support.
Recommended Products for Shift Workers
| Product | Best Use for Shift Workers | Timing |
|---|---|---|
| CBD+CBN+Melatonin Gummies | Pre-daytime sleep for night/rotating shift; circadian phase support | 60–90 min before intended sleep start |
| Broad Spectrum CBD Oil | Pre-shift anxiety management OR pre-sleep support; adjustable dosing | 30 min before shift (low dose) OR 30–45 min pre-sleep |
| Broad Spectrum Softgels | Daily ECS baseline maintenance; rotating schedule chronic support | Consistent time daily (anchor to personal rhythm, not clock time) |
| Elderberry Gummies | Immune support; systemic inflammation management | Morning (personal time, not clock time) |
| CBD Muscle & Joint Cream | Physical recovery for physically demanding shift work roles | Post-shift as needed |
| Broad Spectrum Gummies | Daytime anxiety and stress management on off days | As needed during waking hours |
| Full Spectrum Berry Gummies | Entourage effect support; deeper sleep quality on extended off periods | 60 min before sleep |
Drug Interaction Considerations for Shift Workers
Shift workers often take medications relevant to conditions that are overrepresented in this population. Key interactions to discuss with a healthcare provider:
| Medication / Substance | Interaction Risk | Notes |
|---|---|---|
| Modafinil / Armodafinil | MODERATE | CYP3A4 competition — CBD may increase modafinil exposure; discuss with provider |
| Melatonin (OTC) | LOW | Already included in CBD+CBN+Melatonin product; avoid doubling doses |
| SSRIs / SNRIs | MODERATE | CYP2D6 / CYP2C19 inhibition — elevated in shift worker population; discuss with provider |
| Antihypertensives | MODERATE CAUTION | Cardiovascular risk elevated in shift workers; various metabolic pathways affected |
| Alcohol | HIGH RISK | Common shift worker coping mechanism; worsens sleep architecture and REM; CBD should not be combined with alcohol for sleep |
| Caffeine | NOT PHARMACOLOGICAL | CBD does not block caffeine; avoid caffeine within 6–8 hours of intended sleep window |
For a comprehensive overview of CBD's interaction profile, see our dedicated CBD oil drug interactions guide.
The Science Supporting CBD for Sleep and Circadian Health
The mechanistic rationale for CBD in SWSD draws on converging lines of research. Russo (2016) proposed the Clinical Endocannabinoid Deficiency (CED) hypothesis — the idea that chronic depletion of ECS tone underlies a cluster of conditions including sleep disorders and chronic stress-related dysfunction.3 SWSD's chronic ECS depletion pattern fits squarely within this framework.
Crippa et al. (2011) characterized CBD's anxiolytic effects through neuroimaging, demonstrating limbic and paralimbic modulation relevant to the anxiety and stress burden of chronic shift work.4 Corroon and Phillips (2018) surveyed CBD users and found sleep and anxiety as the two most common reported use cases, with the majority reporting CBD as effective for their primary concern.5 Capano et al. (2020) found that CBD supplementation significantly improved sleep quality scores in a clinical population, with the effect emerging within the first month of consistent use.6
For the foundational science of CBD and sleep, our dedicated sleep guide covers mechanisms in greater depth. For CBD oil for insomnia specifically, including the distinction between sleep onset and sleep maintenance difficulties, see that dedicated resource.
Dosage Guidance for Shift Workers
Dosage for SWSD-related CBD use differs from occasional or situational use because consistency matters more. The ECS requires sustained supplementation to restore depleted tone — particularly for rotating schedule workers in a state of perpetual desynchrony. For comprehensive dosage guidance including weight-based starting points and titration protocols, see our CBD oil dosage guide.
General starting framework for shift workers:
Daily baseline (Softgels or Oil): 15–25mg daily at a consistent personal time, regardless of shift schedule. Consistency of timing — even imperfect timing — is more beneficial than variable high doses. The goal is ECS tone maintenance, not acute effect.
Pre-sleep acute support (CBD+CBN+Melatonin Gummies): One to two gummies (typically 10–20mg CBD + CBN + low-dose melatonin) taken 60–90 minutes before intended daytime sleep. Timing relative to your personal sleep window matters more than clock time.
Pre-shift anxiety support (low-dose Oil): 10–15mg Broad Spectrum Oil sublingually, 30 minutes before shift start. This range may provide mild anxiolytic and alertness-supporting effects without sedation at low doses.
Frequently Asked Questions
Does CBD oil help with shift work sleep disorder?
The evidence base is indirect but mechanistically plausible. CBD oil interacts with the endocannabinoid system, which plays a documented role in sleep regulation, HPA axis modulation, and inflammatory response — all of which are chronically disrupted in SWSD. Clinical studies on CBD for sleep and anxiety (Blessing et al. 2015; Shannon et al. 2019; Capano et al. 2020) show meaningful improvements in sleep quality and anxiety measures, though none have studied SWSD populations specifically. The chronic ECS depletion model of SWSD suggests consistent daily CBD use could restore ECS tone and support better sleep architecture, anxiety management, and recovery. It is not a cure for the circadian disruption itself, but it addresses several downstream consequences of chronic SWSD.
When should shift workers take CBD oil — before sleeping or before their shift?
Both, potentially, but with different products and for different purposes. Before daytime sleep: CBD+CBN+Melatonin Gummies 60–90 minutes before intended sleep onset, timed to your actual sleep window (not clock time). Before a shift: a low dose (10–15mg) of Broad Spectrum CBD Oil 30 minutes before shift start may help with pre-shift anxiety, without causing sedation at low doses. The third timing — daily baseline — uses Softgels at a consistent personal time each day to maintain ECS tone regardless of schedule variability.
Can CBD oil help me sleep during the day after a night shift?
Yes, and this is one of the most practically useful applications of CBD for shift workers. Daytime sleep after a night shift faces three compounding obstacles: circadian resistance (the biological drive to be awake during daylight hours), social noise and light intrusion, and difficulty maintaining sleep through the full required duration. CBD oil and CBD+CBN+Melatonin products address the circadian resistance component — CBD's anxiolytic and GABAergic effects reduce the hyperarousal that makes daytime sleep difficult, while melatonin provides the phase-appropriate sleep onset signal. CBD alone supports sleep architecture by potentially increasing slow-wave sleep. Combine these with behavioral strategies (blackout curtains, white noise, blue-light glasses on the commute home) for maximum effect.
Is CBD oil or melatonin better for shift workers?
They serve distinct and complementary roles — neither is categorically better. Melatonin is a circadian signal: it tells the SCN when to initiate the sleep phase and is most powerful when timed correctly relative to the desired sleep window. CBD addresses the sleep architecture and arousal side: it reduces hyperarousal, supports GABA-mediated relaxation, and modulates the anxiety and stress that interfere with sleep onset and maintenance. For most shift workers, the most effective approach combines both, which is why our CBD+CBN+Melatonin Gummies integrate all three components — CBD for sleep architecture, CBN for deeper rest, and melatonin for circadian timing — into a single pre-sleep product.
Does CBD oil help with the fatigue from shift work?
CBD oil addresses fatigue primarily through improving sleep quality rather than by providing a direct stimulant effect. By improving daytime sleep depth and duration for night shift workers, and reducing the anxiety-driven hyperarousal that prevents restorative sleep, CBD can reduce the fatigue burden over time. CBD is also not sedating at low doses for most people — some users report mild alerting effects at 10–15mg, which may reduce the cognitive fog that accompanies shift work fatigue. However, CBD is not a caffeine replacement or wakefulness agent, and should not be positioned as one. For persistent severe fatigue, reviewing sleep quality, evaluating for comorbid obstructive sleep apnea (common in shift workers), and consulting a sleep specialist are important steps. See also: CBD oil for fatigue.
Can CBD oil help with the anxiety and depression that comes with shift work?
This is one of CBD oil's most relevant applications for shift workers, and one of the more evidence-supported use cases. CBD's 5-HT1A agonism, HPA axis modulation, and reduction in amygdala hyperreactivity (documented in neuroimaging studies by Crippa et al., 2011) are mechanistically relevant to the anxiety and dysthymia that accompany chronic social desynchrony and sleep deprivation. Shannon et al. (2019) found clinically meaningful improvements in both anxiety and sleep scores in a series of patients using CBD, with effects emerging within the first month. For shift workers, CBD addresses both the psychological burden directly and the sleep deprivation that compounds mood disruption. See our guides on CBD oil for anxiety and CBD oil for depression for detailed mechanism discussions.
How is CBD oil for shift work different from CBD oil for jet lag?
The distinction is fundamental and worth understanding clearly. Jet lag is an acute, transient disruption of an otherwise healthy circadian system. The clock is out of phase with the local time zone; it will self-correct within days to two weeks without intervention. CBD for jet lag provides acute sleep support during a temporary disruption to a functional ECS. Shift work sleep disorder is chronic, ongoing, and structurally embedded in a person's livelihood. It does not self-resolve. The ECS itself is chronically depleted — not just acutely disrupted — after months and years of shift work. The CBD strategy therefore shifts from acute situational support (jet lag) to consistent daily ECS restoration and damage mitigation (SWSD). Rotating schedule workers in particular should think of CBD as an ongoing maintenance strategy rather than a situational tool. For the jet lag comparison in detail, see our CBD oil for jet lag guide.
Can CBD oil reduce the long-term health risks of shift work?
This is an important question to answer honestly. CBD cannot eliminate the long-term health risks of shift work — those are driven primarily by persistent circadian misalignment that CBD does not resolve. What CBD may do is mitigate several downstream consequences. By improving sleep quality and duration, CBD supports better metabolic, cardiovascular, and immune outcomes — all of which degrade with chronic sleep deprivation. By reducing systemic inflammation through CB2-mediated and cytokine-modulating pathways, CBD addresses the elevated inflammatory load that is a primary cardiovascular and metabolic risk driver in shift workers. By supporting anxiety and stress management, CBD may reduce the HPA hyperactivation that is independently harmful to metabolic and cardiovascular health. These are meaningful support mechanisms, but they do not make shift work physiologically equivalent to day work. Whenever possible, schedule modifications — fixed rather than rotating schedules, longer rotation intervals, clockwise rotation — provide the most meaningful risk reduction.
Is CBD oil safe to take before a shift to help with alertness?
At low doses (10–15mg), CBD oil is generally non-sedating and may have mild alerting or anxiolytic effects that support functional alertness during the early part of a shift. Some users report reduced pre-shift anxiety and improved focus clarity at low doses. However, CBD is not a reliable wakefulness agent and should not be used as a primary strategy for shift alertness, particularly for safety-critical roles. Effects vary significantly between individuals, and some people experience sedation even at low doses. If you are new to CBD and need to be sharply alert for work, start with a very low dose (5–10mg) on an off day to gauge your personal response before using it before a shift. CBD is best positioned for shift workers as a sleep quality enhancer and chronic ECS support tool, not a wakefulness medication. For shift-related excessive sleepiness, a sleep medicine specialist can evaluate whether modafinil or other evidence-based interventions are appropriate.
How much CBD oil should shift workers take?
Dosage for shift workers has three distinct components. First, a daily baseline for ECS maintenance: 15–25mg via Softgels or Broad Spectrum Oil, taken at a consistent personal time daily. Second, pre-sleep acute support: one to two CBD+CBN+Melatonin Gummies (10–20mg CBD range) 60–90 minutes before your personal sleep window. Third, optional pre-shift anxiety support: 10–15mg Oil sublingually 30 minutes before shift. Start low, assess response over two to four weeks, and titrate upward gradually if needed. Weight, individual ECS sensitivity, concurrent medications, and the severity of SWSD symptoms all influence optimal dosing. For individualized guidance, consult our CBD oil dosage guide.
Related Articles
- CBD Oil for Jet Lag
- CBD Oil for Sleep: Complete Guide
- CBD Oil for Insomnia
- CBD Oil for Anxiety
- CBD Oil for Fatigue
- CBD Oil Dosage Guide
References
- Blessing EM, Steenkamp MM, Manzanares J, Marmar CR. Cannabidiol as a Potential Treatment for Anxiety Disorders. Neurotherapeutics. 2015;12(4):825-836. PMID: 26341731
- Shannon S, Lewis N, Lee H, Hughes S. Cannabidiol in Anxiety and Sleep: A Large Case Series. Perm J. 2019;23:18-041. PMID: 30624194
- Russo EB. Clinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes. Cannabis Cannabinoid Res. 2016;1(1):154-165. PMID: 28861491
- Crippa JA, Derenusson GN, Ferrari TB, et al. Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. J Psychopharmacol. 2011;25(1):121-130. PMID: 20829306
- Corroon J, Phillips JA. A Cross-Sectional Study of Cannabidiol Users. Cannabis Cannabinoid Res. 2018;3(1):152-161. PMID: 30014049
- Capano A, Weaver R, Burkman E. Evaluation of the effects of CBD hemp extract on opioid use and quality of life indicators in chronic pain patients: a prospective cohort study. Postgrad Med. 2020;132(1):56-61. PMID: 31711352
Medical Disclaimer
This article is for informational purposes only and does not constitute medical advice. CBD products have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or condition, including shift work sleep disorder. If you experience chronic sleep disruption related to your work schedule, consult a sleep medicine specialist. Do not combine CBD with prescription wakefulness agents or other medications without consulting your healthcare provider. Individual results vary.
